A weird one. Just putting it out there to see if anyone else has noticed anything similar.
I have an experienced user, who was editing a page in the admin interface (v5.1.4.0) using a recent Firefox (don't know the exact version).
They had a div with a lot of content, and needed to split it up, so they created a new div at the top of the page, cut the first section, pasted it into the new div, but when they 'Save Changes', the rest of the content in the first div vanished. The new div is OK, but the original div was saved empty.
Fortunately, I was able to dig it out of the system logs and restore the html for the panicked user, but then it happened again. Exactly the same. There was something about this simple cut and paste process which was causing the wysiwyg to empty the container on save. They experienced this on more than one page, on about 4 or 5 occasions, losing work each time.
I've tried reproducing the issue in some reliable, repeatable way, but cannot. I've heard anecdotally of at least two other users who experienced a similar issue, but again, quite random and virtually impossible to reproduce. The trouble is, by the time its happened, you've destroyed the evidence!